Clinical and biochemical assessment of the effect of glutamine in management of radiation induced oral mucositis in patients with head and neck cancer: Randomized controlled clinical trial

Ibrahim, Suzan S; Hassanein, Fatma E A; Zaky, Hany W; Gamal Almalahy, Hadeel;

Abstract


This study aimed to evaluate the effect of oral glutamine suspension on salivary levels of transforming growth factor beta 1 (TGF-β1), a cytokine involved in inflammation and Tumor progression, and the severity of radiation-induced oral mucositis (RIOM) in head and neck cancer patients. This is the first study to investigate the impact of glutamine on TGF-β1 levels in head and neck cancer patients with radiation induced oral mucositis (RIOM).


Other data

Title Clinical and biochemical assessment of the effect of glutamine in management of radiation induced oral mucositis in patients with head and neck cancer: Randomized controlled clinical trial
Authors Ibrahim, Suzan S; Hassanein, Fatma E A; Zaky, Hany W; Gamal Almalahy, Hadeel 
Keywords Glutamine; Head and neck cancer; Oral mucositis; TGF-β1; Transforming growth factor beta 1
Issue Date Jun-2024
Journal Journal of stomatology, oral and maxillofacial surgery 
ISSN 24687855
DOI 10.1016/j.jormas.2024.101827
PubMed ID 38493953
Scopus ID 2-s2.0-85188426293

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