Targeting the ubiquitin proteasome system in cancer stem cells
Atta, Hind; Kamal, Mohamed M; Prof. Hamdy, Nadia M.; Kassem, Dina;
Abstract
Over the past few years there has been an alarming burst of cancer burden worldwide. Cancer stem cells (CSCs) act as hidden devils within tumors, rendering cancer therapy a strenuous goal. Recently, the ubiquitin proteasome system (UPS) was proved to be an essential contributor to the CSC phenotype. This forum article aims to outline new strategies/technologies targeting UPS modulation in CSCs as a potential novel modality for efficient cancer therapy.
Other data
| Title | Targeting the ubiquitin proteasome system in cancer stem cells | Authors | Atta, Hind; Kamal, Mohamed M; Prof. Hamdy, Nadia M. ; Kassem, Dina | Issue Date | Feb-2025 | Journal | Trends in cell biology | Volume | 35 | Issue | 2 | Start page | 97 | End page | 101 | ISSN | 09628924 | DOI | 10.1016/j.tcb.2024.11.011 | PubMed ID | 39721924 | Scopus ID | 2-s2.0-85212980558 |
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