ANTIBODY DIRECTED ENZYME PRODRUG THERAPY: Molecular Studies on Carboxypeptidase G2; Production by DNA Shuffling of Novel Variants of CPG2 for more efficient cancer treatment
Fatma Baiuomy Rashedy Abd-Allah;
Abstract
Glucarpidase (former name: carboxypeptidase G2, or CPG2) is a bacterial
enzyme that is widely used in detoxification of the cytotoxic drug, methotrexate, and in
Antibody Directed Enzyme Prodrug Therapy (ADEPT) for cancer treatment. In this
study we report
enzyme that is widely used in detoxification of the cytotoxic drug, methotrexate, and in
Antibody Directed Enzyme Prodrug Therapy (ADEPT) for cancer treatment. In this
study we report
Other data
| Title | ANTIBODY DIRECTED ENZYME PRODRUG THERAPY: Molecular Studies on Carboxypeptidase G2; Production by DNA Shuffling of Novel Variants of CPG2 for more efficient cancer treatment | Other Titles | علاج مرض السرطان بإستخدام جسم مضاد موجه ومحمل بإنزيم الكربوكسى بيبتيديزجى 2: دراسات جزيئية على هذا الانزيم؛ وانتاج مشابهات لهذا الانزيم ذو كفاءة اعلى من خلال تكنولوجيا قصوخلط وإعادة لصق الجين. | Authors | Fatma Baiuomy Rashedy Abd-Allah | Keywords | ANTIBODY DIRECTED ENZYME PRODRUG THERAPY: Molecular Studies on Carboxypeptidase G2; Production by DNA Shuffling of Novel Variants of CPG2 for more efficient cancer treatment | Issue Date | 2010 | Description | Glucarpidase (former name: carboxypeptidase G2, or CPG2) is a bacterial enzyme that is widely used in detoxification of the cytotoxic drug, methotrexate, and in Antibody Directed Enzyme Prodrug Therapy (ADEPT) for cancer treatment. In this study we report |
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