Browsing by Department Department of Pharmaceutical Chemistry - Pharmacy


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Showing results 79 to 98 of 176 < previous   next >
Issue DateTitleAuthor(s)
Mar-2022Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessmentElgiushy, Hossam R; Mohamed, Sameh H; Sawaf, Hussein; Hassan, Zeinab; Abou-Taleb, Nageh A; El-Labbad, Eman M; Hassan, Ashraf S; Abouzid, Khaled A M; Abouzid, Khaled ; Ali Taha, Heba
Dec-2018Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modelingAdel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid 
8-Mar-2022Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluationMansour, Mai A; Oraby, Mamdouh A; Muhammad, Zeinab A; Lasheen, Deena ; Gaber, Hatem M; Khaled A M Abouzid 
2019Identification of novel pyrazole and benzimidazole based derivatives as PBP2a inhibitors: Design, synthesis, and biological evaluationShalaby, Menna-Allah; Dokla, Eman ; Serya, Rabah ; Abouzid, Khaled 
2018Imidazo[2',1':2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling studyEwida, Menna A; Abou El Ella, Dalal ; Lasheen, Deena S. ; Ewida, Heba A; El-Gazzar, Yomna I; El-Subbagh, Hussein I
Jul-2013In silico design: extended molecular dynamic simulations of a new series of dually acting inhibitors against EGFR and HER2Ahmed, Marawan; Sadek, Maiada M; Abouzid, Khaled ; Wang, Feng
4-May-2016Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivativesEldehna, Wagdy M; Abou-Seri, Sahar M; El Kerdawy, Ahmed M; Ayyad, Rezk R; Hamdy, Abdallah M; Ghabbour, Hazem A; Ali, Mamdouh M; Abou El Ella, Dalal 
1-Dec-2021Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancerDokla, Eman ; Abdel-Aziz, Amal Kamal; Milik, Sandra N.; Mahmoud, Amr H.; Saadeldin, Mona Kamal; McPhillie, Martin J.; Minucci, Saverio; Khaled A M Abouzid 
15-Jul-2015Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular dockingEldehna, Wagdy M; Fares, Mohamed; Ibrahim, Hany S; Aly, Mohamed H; Zada, Suher; Ali, Mamdouh M; Abou-Seri, Sahar M; Abdel-Aziz, Hatem A; Abou El Ella, Dalal 
1-Jun-2022Induction of apoptosis using ATN as a novel Yes-associated protein inhibitor in human oral squamous cell carcinoma cellsChu, Po Chen; Dokla, Eman ; Hu, Jing Lan; Weng, Jing Ru
2022Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: A case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitorsMilik, SN; Abdel-Aziz, AK; El-Hendawy, MM; El-Gogary, RI; Saadeldin, MK; Minucci, S; Klein, CD; Abouzid, Khaled 
1-Apr-2012Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivativesIsmail, Mohamed A H; Abou El Ella, Dalal ; Khaled A M Abouzid ; Mahmoud, Amr H
1-Jan-1984Investigations on the Stability of Famprofazon N‐OxideAbou El Ella, Dalal ; Neugebauer, Michael; Eid, Attiat; Ebied, Mohamed Y.; Rücker, Gerhard
1-Sep-2020An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic propertiesMohamed, Sameh H; Elgiushy, Hossam R; Hammad, Sherif F; Abou-Taleb, Nageh A; A M Abouzid, Khaled; Abouzid, Khaled ; Hassan, Zeinab; Ali Taha, Heba
1-Sep-2011Labeling and Biological Evaluation of 99mTc-Cefotaxime for infective Inflammation DiagnosisM. A. Motaleb; A. A. El Mohty; M. A. El Garhy; Mohamed abdel Hamid Ismail; Abouzid, Khaled ; Tamer M. Sakr
15-Feb-2006Ligand design and synthesis of new imidazo[5,1-b]quinazoline derivatives as alpha1-adrenoceptor agonists and antagonistsIsmail, Mohamed A H; Aboul-Enein, Mohamed N Y; Abouzid, Khaled ; Serya, Rabah A T
1-Dec-2013Ligand design, synthesis and biological anti-HCV evaluations for genotypes 1b and 4a of certain 4-(3- & 4-[3-(3,5-dibromo-4-hydroxyphenyl)-propylamino] phenyl) butyric acids and 3-(3,5-dibromo-4-hydroxyphenyl)-propylamino- acetamidobenzoic acid estersIsmail, Mohamed Abdel Hamid; Mohamed, Nasser Saad; Dokla, Eman ; Khaled A M Abouzid 
2021Lipid polymer hybrid nanocarriers as a combinatory platform for different anti-SARS-CoV-2 drugs supported by computational studiesAbdel-Bar, Hend Mohamed; Abdallah, Inas A.; Fayed, Marwa A. A.; Moatasim, Yassmin; Mostafa, Ahmed; El-Behairy, Mohammed Farrag; Elimam, Hanan; Elshaier, Yaseen A. M. M.; Abouzid, Khaled 
2009Lonazolac analogues: molecular modeling, synthesis, and in vivo anti-inflammatory activityIsmail, MAH; Lehmann, J; Abou El Ella, D.A. ; Albohy, A; Abouzid, Khaled 
Nov-2017Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer ActivitiesGhith, Amna; Ismail, Nasser S M; Youssef, Khairia; Abouzid, Khaled