Abouzid, Khaled

khaled.abouzid@pharma.asu.edu.eg

Department of Pharmaceutical Chemistry - Pharmacy
Interests: Anticancer drug discovery, design and synthesis, Antimicrobial,
Internal ID: rp12178
  • 2,885 Scopus Citations
  • 592 PubMed Citations

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Full Name
Abouzid, Khaled
 
 
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Biography
Dr. Khaled Abouzid is a Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Prominent Scholar in Drug Discovery, Co-founding Director of Center of Drug Discovery and Development Research ASU He was nominated as the Acting Dean of the Faculty of Pharmacy, University of Sadat City from 8-2018 to 8-2022. He is currently a member of national pharmaceutical chemistry promotion committee
Dr. Abouzid’s research is directed towards drug discovery of bioactive small molecules with special emphasis on cannabinoids, targeted anticancer, anti-inflammatory, anti-viral anti-microbial agents and enzyme inhibitors. He has published over 150 research papers, two books and filed 14 patents in medicinal chemistry. He has Scopus H index of 28. He has supervised over 100 Master and PhD students in 7 universities. Dr Abouzid has research collaborations with German, British, Swedish, Canadian and US universities. He has also organized and presided over 34 international symposia and conferences.
Dr. Abouzid obtained his B.Sc. degree in Pharmaceutical Sciences from Cairo University in 1985, and his PhD. joint degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University and School of Pharmacy University of Connecticut, USA.
Dr. Abouzid started his career in 1995 as a lecturer of Organic Chemistry at Cairo University, Faculty of Pharmacy. In 2001, he moved to the Department of Pharmaceutical Chemistry, Ain Shams University, and was promoted to Associate Professor in 2003. He did postdoctoral work with Professor Jochen Lehman of the Friedrich-Schiller-Universität Jena, Germany.

Publications

Results 101-120 of 133 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
101Nov-2012A highly selective structure-based virtual screening model of Palm I allosteric inhibitors of HCV Ns5b polymerase enzyme and its application in the discovery and optimization of new analoguesMahmoud, Amr H; Ismail, Mohamed A H; Abouzid, Khaled ; Abou El Ella, Dalal 
102Aug-2012Synthesis and anti-proliferative activity of substituted-anilinoquinazolines and its relation to EGFR inhibitionEl Ella, D A A; Saleh, K A; Hassan, M; Hamdy, N; El-Araby, M E; Abouzid, Khaled 
1031-Apr-2012Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivativesIsmail, Mohamed A H; Abou El Ella, Dalal ; Khaled A M Abouzid ; Mahmoud, Amr H
1042012Synthesis and evaluation of anti-proliferative activity of 1,4-disubstituted phthalazinesAbouzid, Khaled ; Khalil, NA; Ahmed, E.M. 
1052012DESIGN, SYNTHESIS AND VIRTUAL SCREENING OF CERTAIN 2-PYRAZOLIN-5-ONE AND PYRAZOLIDINE-3, 5-DIONE DERIVATIVES AS POTENTIAL PPAR gamma AGONISTSIsmaila, MAH; El Ella, DAA; Abouzid, Khaled ; Jaballah, M
1061-Nov-2011Baclofen ester and carbamate prodrug candidates: a simultaneous chromatographic assay, resolution optimized with DryLabHanafi, Rasha; Mosad, Salwa; Abouzid, Khaled ; Niess, Raimund; Spahn-Langguth, Hilde
1071-Sep-2011Preparation of 99mTc-ceftazidime as a model of infection imaging agentM. A. Motaleb; A. A. El Mohty; M. A. El Garhy; Mohamed abdel Hamid Ismail; Abouzid, Khaled ; Tamer M. Sakr
1081-Sep-2011Labeling and Biological Evaluation of 99mTc-Cefotaxime for infective Inflammation DiagnosisM. A. Motaleb; A. A. El Mohty; M. A. El Garhy; Mohamed abdel Hamid Ismail; Abouzid, Khaled ; Tamer M. Sakr
109Feb-2011Molecular modeling study and synthesis of quinazolinone-arylpiperazine derivatives as α1-adrenoreceptor antagonistsAbou-Seri, Sahar Mahmoud; Abouzid, Khaled ; Abou El Ella, Dalal 
1102011Optimization of Benzoisothiazole dioxide inhibitory activity of the NS5B polymerase of HCV genotype 4 using ligand-steered homological modeling, reaction-driven scaffold-hopping and Enovo workflowMahmoud, Amr Hamed; Abouzid, Khaled ; El Ella, Dalal Abd El Rahman Abou; Hamid Ismail, Mohamed Abdel
11115-Dec-2010Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligandsOsman, Noha A; Mahmoud, Amr H; Allarà, Marco; Niess, Raimund; Khaled A M Abouzid ; Di Marzo, Vincenzo; Abadi, Ashraf H
1122010Computer - based drug design, synthesis and biological evaluation of new pyrimidinone derivatives linked to arylpiperazine and 2 '-carbethoxy-biphenylylmethyl moeities as alpha(1)-adrenoceptor antagonists and angiotensin II AT(1) receptor antagonistsIsmail, MAH; Abouzid, Khaled ; Al-Ansary, GHA; Abou El Ella, Dalal 
1132010Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitorsAbouzid, Khaled ; Khalil, NA; Ahmed, E.M. ; El-Latif, HAA; El-Araby, ME
1142010Organic synthesis and biological evaluation of novel "3+1" mixed ligands of technetium-99m Gabapentin as receptor imaging agentsAmin, AM; Abouzid, Khaled ; Bayoumi, NA; Abd El-hamid, M
11515-Aug-2009Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitorsAbadi, Ashraf H; Ibrahim, Tamer M; Khaled A M Abouzid ; Lehmann, Jochen; Tinsley, Heather N; Gary, Bernard D; Piazza, Gary A
11615-May-2009ACE inhibitors hypothesis generation for selective design, synthesis and biological evaluation of 3-mercapto-2-methyl-propanoyl-pyrrolidine-3-imine derivatives as antihypertensive agentsIsmail, Mohamed A H; Nabil Aboul-Enein, M; Abouzid, Khaled ; Ismail, Nasser S M; Abou El Ella, Dalal 
1172009Lonazolac analogues: molecular modeling, synthesis, and in vivo anti-inflammatory activityIsmail, MAH; Lehmann, J; Abou El Ella, D.A. ; Albohy, A; Abouzid, Khaled 
11815-Aug-2008Design, synthesis and in vitro antitumor activity of 4-aminoquinoline and 4-aminoquinazoline derivatives targeting EGFR tyrosine kinaseAbouzid, Khaled ; Shouman, Samia
11915-May-2008Novel anti-inflammatory agents based on pyridazinone scaffold; design, synthesis and in vivo activityAbouzid, Khaled ; Bekhit, Salma A
1201-Jan-2008Pyridazinone derivatives: design, synthesis, and in vitro vasorelaxant activityAbouzid, Khaled ; Abdel Hakeem, Maha; Khalil, Omnya; Maklad, Yosria