Abouzid, Khaled

khaled.abouzid@pharma.asu.edu.eg

Department of Pharmaceutical Chemistry - Pharmacy
Interests: Anticancer drug discovery, design and synthesis, Antimicrobial,
Internal ID: rp12178
  • 2,885 Scopus Citations
  • 592 PubMed Citations

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Full Name
Abouzid, Khaled
 
 
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Biography
Dr. Khaled Abouzid is a Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Prominent Scholar in Drug Discovery, Co-founding Director of Center of Drug Discovery and Development Research ASU He was nominated as the Acting Dean of the Faculty of Pharmacy, University of Sadat City from 8-2018 to 8-2022. He is currently a member of national pharmaceutical chemistry promotion committee
Dr. Abouzid’s research is directed towards drug discovery of bioactive small molecules with special emphasis on cannabinoids, targeted anticancer, anti-inflammatory, anti-viral anti-microbial agents and enzyme inhibitors. He has published over 150 research papers, two books and filed 14 patents in medicinal chemistry. He has Scopus H index of 28. He has supervised over 100 Master and PhD students in 7 universities. Dr Abouzid has research collaborations with German, British, Swedish, Canadian and US universities. He has also organized and presided over 34 international symposia and conferences.
Dr. Abouzid obtained his B.Sc. degree in Pharmaceutical Sciences from Cairo University in 1985, and his PhD. joint degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University and School of Pharmacy University of Connecticut, USA.
Dr. Abouzid started his career in 1995 as a lecturer of Organic Chemistry at Cairo University, Faculty of Pharmacy. In 2001, he moved to the Department of Pharmaceutical Chemistry, Ain Shams University, and was promoted to Associate Professor in 2003. He did postdoctoral work with Professor Jochen Lehman of the Friedrich-Schiller-Universität Jena, Germany.

Publications

Results 41-60 of 133 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
412019Design, synthesis and molecular docking of novel pyrazolo[1,5-a][1,3,5]triazine derivatives as CDK2 inhibitorsOudah, Khulood H; Najm, Mazin A A; Samir, Nermin; Serya, Rabah ; Khaled A M Abouzid 
422019Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activityElsayed, Nevine M Y; Serya, Rabah ; Tolba, Mai ; Ahmed, Marawan; Barakat, Khaled; Abou El Ella, Dalal ; Khaled A M Abouzid 
43Dec-2018Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modelingAdel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid 
4413-Nov-2018Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axisGe, Xin; Pan, Min-Hong; Wang, Lin; Li, Wei; Jiang, Chengfei; He, Jun; Abouzid, Khaled ; Liu, Ling-Zhi; Shi, Zhumei; Jiang, Bing-Hua
45Sep-2018Pyrrolopyrimidine, A Multifaceted Scaffold in Cancer Targeted TherapyAdel, Mai; Serya, Rabah A T; Lasheen, Deena S. ; Abouzid, Khaled 
46Sep-2018Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancerHesham, Heba M; Lasheen, Deena S. ; Khaled A M Abouzid 
4715-Jul-2018Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinomaShahin, Mai I; Roy, Joyeeta; Hanafi, Maha; Wang, Dongyao; Luesakul, Urarika; Chai, Yifeng; Muangsin, Nongnuj; Lasheen, Deena S. ; Neamati, Nouri; Khaled A M Abouzid ; Abou El Ella, Dalal 
4815-Jul-2018Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitorsMilik, Sandra N; Abdel-Aziz, Amal Kamal; Serya, Rabah ; Minucci, Saverio; Lasheen, Deena S. ; Khaled A M Abouzid 
491-Jun-2018Design, synthesis and 3D QSAR based pharmacophore study of novel imatinib analogs as antitumor-apoptotic agentsFawzy, Iten M; Youssef, Khairia M; Lasheen, Deena S. ; Ismail, Nasser Sm; Abouzid, Khaled 
5025-May-2018Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant gram-positive bacterial pathogensElAwamy, Moustafa; Mohammad, Haroon; Hussien, Abdelrahman; Abutaleb, Nader S; Hagras, Mohamed; Serya, Rabah ; Taher, Azza T; Seleem, Mohamed N; Mayhoub, Abdelrahman S; Khaled A M Abouzid 
512018Acrylamide moiety, a Valuable Fragment in Medicinal Chemistry: Insight into Synthetic Methodologies, Chemical Reactivity and Spectrum of Biological Activities of Acrylamide DerivativesElgiushy, Hossam; Hammad, Sherif; Hassan, Ashraf; Aboutaleb, Nageh; Abouzid, Khaled 
522018Design, synthesis, molecular docking study, and biological evaluation of salicylaldimine derivatives as potential histone deacetylases inhibitors (HDACi) and anticancer agentsHesham, Heba; Lasheen, Deena S. ; Abouzid, Khaled 
5315-Dec-2017How to train your inhibitor: Design strategies to overcome resistance to Epidermal Growth Factor Receptor inhibitorsMilik, Sandra N; Lasheen, Deena S; Serya, Rabah ; Abouzid, Khaled A M; Khaled A M Abouzid 
54Nov-2017Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer ActivitiesGhith, Amna; Ismail, Nasser S M; Youssef, Khairia; Abouzid, Khaled 
557-Jul-2017Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activitiesAbouzid, Khaled ; Al-Ansary, Ghada H; El- naggar, Abeer 
566-Jul-2017Synthesis, ADMET Properties, and Biological Evaluation of Benzothiazole Compounds Targeting Chemokine Receptor 2 (CXCR2)Mehanna, Wesam E; Lu, Tiangong; Debnath, Bikash; Lasheen, Deena S. ; Serya, Rabah A T; Abouzid, Khaled ; Neamati, Nouri
57Mar-2017Pyridazine Based Scaffolds as Privileged Structures in anti-Cancer TherapyJaballah, Maiy Youssef; Serya, Rabah Taha; Abouzid, Khaled 
5830-Jan-2017Click and Release: SO2 Prodrugs with Tunable Release RatesSerya, Rabah ; Khaled A.M.abouzid; Deena S.Lasheen; Xingyue Ji; Binghe Wang; Khaled A M Abouzid 
59Nov-2016Design and Synthesis of 4-Anilinothieno[2,3-d]pyrimidine-Based Compounds as Dual EGFR/HER-2 InhibitorsAbd El Hadi, Soha R; Lasheen, Deena S. ; Hassan, Mahmoud A; Khaled A M Abouzid 
6021-Oct-2016Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionalityOsman, Noha A; Ligresti, Alessia; Klein, Christian D; Allarà, Marco; Rabbito, Alessandro; Di Marzo, Vincenzo; Abouzid, Khaled ; Abadi, Ashraf H