Statistical Modelling and Analysis of Gene Expression Data

Abstract

Genes carry the genetic information and traits of the human. A gene is a distinct portion of a cell’s DNA. A gene corresponds to a sequence of micro-molecules along one or more regions of a DNA. Each gene codes for a specific protein by specifying the order in which amino acids must be joined together. These proteins are then the regulators of all cell’s and tissue functions. Gene expression refers to the activity of the gene, whether a gene is on or off. During the activity of a gene, a special type of molecules is synthesised called mRNA. Hence, the state of the gene is hitched to this mRNA, an active or suppressed gene is covalent to the abundance of mRNA molecules.