Early Cognitive Impairment in Multiple Sclerosis Patients In Relation to Brain Atrophy, Egyptian Sample

Abstract

Finally, standards for a priori reporting of methods must be upheld for cognitive rehabilitation RCTs, including greater transparency for outcomes (e.g., specific scores on specific tests registered on clinicaltrials.gov, rather than nonspecific references to ―cognition‖ or ―memory tests‖). Cognitive rehabilitation researchers are directed to Simons and colleagues47 for a thorough discussion of essential guidelines for the conduct of high-quality cognitive intervention trials (Simons et al ., 2016). We should also promote primary prevention of cognitive decline, in part through interventions and healthy lifestyles that promote brain maintenance. Candidate modifiable lifestyle factors to build or maintain brain reserve include physical exercise, mentally active lifestyles (cognitive reserve), management of cardiovascular risk factors and other co-morbidities, smoking cessation, and stress management (Kappus et al., 2016)