Coenzyme Q10 phospholipidic vesicular formulations for treatment of androgenic alopecia: ex vivo permeation and clinical appraisal
Mamdouh Kamel El Zaafarany, Ghada; Abdel-Aziz, Rasha T A; Montaser, Mahmoud Hamdy Ahmed; Nasr, Maha;
Abstract
Coenzyme Q10 (CoQ10) is an antioxidant molecule with anti-aging activity on human hair, and because of its pharmaceutical limitations such as large molecular weight, high lipophilicity and poor water solubility, its therapeutic effectiveness has been hampered. Therefore, different vesicular nanocarriers were developed in the current work, for enhancement of the skin penetration of CoQ10 for treatment of androgenic alopecia.
Other data
| Title | Coenzyme Q10 phospholipidic vesicular formulations for treatment of androgenic alopecia: ex vivo permeation and clinical appraisal | Authors | Mamdouh Kamel El Zaafarany, Ghada ; Abdel-Aziz, Rasha T A; Montaser, Mahmoud Hamdy Ahmed; Nasr, Maha | Keywords | transethosomes;Coenzyme q10;androgenic alopecia;cerosomes;ethosomes;liposomes;transfersomes | Issue Date | 2021 | Publisher | TAYLOR & FRANCIS LTD | Journal | Expert opinion on drug delivery | ISSN | 1742-5247 | DOI | 10.1080/17425247.2021.1936497 | PubMed ID | 34047661 | Scopus ID | 2-s2.0-85107558870 | Web of science ID | WOS:000658563800001 |
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