Design, synthesis and 3D QSAR based pharmacophore study of novel imatinib analogs as antitumor-apoptotic agents
Fawzy, Iten M; Youssef, Khairia M; Lasheen, Deena S.; Ismail, Nasser Sm; Abouzid, Khaled;
Abstract
Imatinib possesses various mechanisms for combating cancer, making the development of imatinib analogs an attractive target for cancer research.
Other data
| Title | Design, synthesis and 3D QSAR based pharmacophore study of novel imatinib analogs as antitumor-apoptotic agents | Authors | Fawzy, Iten M; Youssef, Khairia M; Lasheen, Deena S. ; Ismail, Nasser Sm; Abouzid, Khaled | Keywords | protein kinase;3D QSAR pharmacophore;caspase-3 induction;cytotoxicity;imatinib | Issue Date | 1-Jun-2018 | Publisher | FUTURE SCI LTD | Journal | Future medicinal chemistry | Volume | 10 | Issue | 12 | ISSN | 1756-8919 | DOI | 10.4155/fmc-2017-0242 | PubMed ID | 29788766 | Scopus ID | 2-s2.0-85048632090 | Web of science ID | WOS:000437056400005 |
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