Browsing by Author Eman A. E. El-Helw

Showing results 1 to 42 of 42
Issue DateTitleAuthor(s)
20192-Cyano-N '-[(1,3-diphenyl-1H-pyrazol-4-yl)methylidene]acetohydrazide in the Synthesis of Nitrogen HeterocyclesAzab, ME; Sayed K. Ramadan ; Eman A. E. El-Helw 
20223-Aryl/hetaryl-2-cyanoacryloyl chlorides: Synthesis and Reactions with Binucleophiles Targeting HeterocyclesEl-Ziaty, Ahmed ; S.K. Ramadan ; Eman A.E. El-Helw 
1-Jan-2021Acryloyl isothiocyanate skeleton as a precursor for synthesis of some novel pyrimidine, triazole, triazepine, thiadiazolopyrimidine and acylthiourea derivatives as antioxidant agentsEl-Badawy, AA; Elgubbi, AS; Eman A.E. El-Helw 
2014Antioxidant activity of heterocyclic compounds derived from 4-(4-acetamidophenyl)-4-oxobut-2-enoic acidM. S. Salem ; El-Helw, Eman ; Dalal B. Guirguis ; Eman A. E. El-Helw ; Mosad A. Ghareeb ; Hamed A. Y. Derbala 
2019Antioxidant activity of some N-heterocycles derived from 2-(1-(2-oxo-2H-chromen-3-yl)ethylidene) hydrazinecarbothioamideSallam, H.A. ; Elgubbi, AS; Eman A. E. El-Helw 
13-May-2025Antioxidant activity, molecular docking, and modeling pharmacokinetics study of some benzo[f]quinoline candidatesEl-Fagal, Sara F; Eman A. E. El-Helw ; El-Bordany, Eman A; Ghareeb, Eman A
Nov-2019Cytotoxic and antimicrobial activities of some novel heterocycles employing 6-(1,3-diphenyl-1H-pyrazol-4-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrileSayed K. Ramadan; Hanan A. Sallam; Eman A. E. El-Helw 
2018Design and Synthesis of some N-Heterocycles Derived from Furyl-2 (3H)-FuranoneRamadan, S. K. ; El-Helw, E. A. E. 
2025Design, Synthesis, Antiproliferative Activity and In Silico Studies of 2-Oxo-1,2-Dihydroquinolin DerivativesEman A. E. El-Helw ; Ghareeb, Eman A.; Mahmoud, Naglaa F. H.; El-Bordany, Eman A.; Soliman, Elsayed A.; El-Khouly, Ahmed; Abouzid, Khaled
2020Development of Chromone-Pyrazole-Based Anticancer AgentsSalem MS, ; Derbala, HAY; Eman A. E. El-Helw 
2019Efficient Microwave-Assisted Synthesis of Some N-Heterocycles Integrated with a Pyrazole MoietySayed K. Ramadan ; Eman A. E. El-Helw 
1-Apr-2021Evaluation of some new heterocycles bearing 2-oxoquinolyl moiety as immunomodulator against highly pathogenic avian influenza virus (H5N8)Morsy, ARI; Hashem, A.I. ; Eman A. E. El-Helw 
1-Jan-2024Facile Synthesis and Antioxidant Activity Screening of Some Novel 3-Substituted Indole DerivativesElgubbi, Amna S.; Alzahrani, Abdullah Y.A.; Eman A. E. El-Helw ; Shaban, Safaa S.
2022Facile Synthesis, Biological Evaluation, DFT Studies and in Silico Prediction ADME/Pharmacokinetics Properties of N-(1-(2-Chlorobenzo[h]Quinolin-3-yl)-1-Substituted-vin-2-yl)Benzamide DerivativesAbdelrahman, AM; Fahmi, AA; Rizk, Sameh Ahmed ; Eman A. E. El-Helw 
2025In Silico ADME, DFT, and Antiproliferative Activity of Pyrazole-based Pyrimidinethione, Triazolethione, and Thiadiazolopyrimidine DerivativesRamadan, Sayed ; Gomha, S. M.; E.A.E. El-Helw 
1-Jan-2021New potential fungicides pyrazole-based heterocycles derived from 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl) acryloyl isothiocyanateRamadan, S.K. ; Ibrahim, NA; El-Kaed, SA; Eman A. E. El-Helw 
31-Jul-2018Proclivity of chromonyloxazolone towards some nitrogen nucleophilesEl-Helw, E. A. E. ; Derbala, Hamed A. ; El-Shahawi, Manal ; Salem, Marwa S. 
1-Jan-2024Some Thiazolopyrimidine Derivatives: Synthesis, DFT, Cytotoxicity, and Pharmacokinetics Modeling StudyRamadan, Sayed ; Alzahrani, Abdullah Y. A.; Eman A. E. El-Helw 
2020Synthesis and anti-rotavirus activity of some nitrogen heterocycles integrated with pyrazole scaffoldEl-Helw, EAE ; Gado, Marwa M ; El-Ziaty, AK
2018Synthesis and antimicrobial activity evaluation of some novel heterocycles derived from chromonyl-2(3H)-furanoneRamadan, Sayed; Eman A. E. El-Helw 
1-Jan-2023Synthesis and antioxidant activity of some pyrazole-based heterocycles using a 2(3H)-furanone building blockYoussef, Youssef M.; Elsayed, Galal A. ; El-Sayed, Amira A.; Hassaballah, Aya I.; Azab, Mohammad ; Eman A. E. El-Helw 
1-Jan-2021Synthesis and antioxidant evaluation of some heterocyclic candidates from 3-(1,3-diphenyl-1H-pyrazol-4-yl)-2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)propenonitrileRamadan, Sayed ; El-Ziaty, Ahmed K.; Eman A. E. El-Helw 
2-Jul-2020Synthesis and antioxidant screening of new 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl amide derivatives and some pyrazole-based heterocyclesSallam, H.A. ; Elgubbi, AS; Eman A. E. El-Helw 
1-Sep-2023Synthesis and antioxidant, antimicrobial, and antiviral activity of some pyrazole-based heterocycles using a 2(3H)-furanone derivativeYoussef, Youssef M.; Azab, Mohammad E.; Elsayed, Galal A. ; El-Sayed, Amira A.; Hassaballah, Aya I.; El-Safty, Mounir M.; Soliman, Reem A.; El-Helw, EAE 
2022Synthesis and Antiproliferative Screening of Some Heterocycles Derived from 4-((5-Chloro-3-Methyl-1-Phenyl-1H-Pyrazol-4-yl)Methylene)-2-Phenyloxazol-5(4H)-OneYoussef, YM; Azab, ME; Elsayed, GA; El-Sayed, AA; Eman A. E. El-Helw 
2-Apr-2020Synthesis and antitumor activity evaluation of some pyrrolone and pyridazinone heterocycles derived from 3-((2-oxo-5-(p-tolyl)furan-3(2H)-ylidene)methyl)quinolin-2(1H)-oneHashem, A.I. ; Eman A.E. El-Helw 
1-Jan-2024Synthesis and Biological Applications of Coumarinyl-ChalconesRamadan, Sayed ; Rizk, Sameh Ahmed ; Eman A. E. El-Helw 
12-Sep-2023Synthesis and cytotoxicity evaluation of novel 1,8-acridinedione derivatives bearing phthalimide moiety as potential antitumor agentsKhatab, Hassan A; Hammad, Sherif F; El-Fakharany, Esmail M; Hashem, Ahmed I. ; El-Helw, EAE 
2025Synthesis and Exploring Antiproliferative Activity of Some Pyrazole-Bearing Heterocycles: DFT, Molecular Docking, and ADME StudyRamadan, Sayed ; Gomha, S. M.; El-Helw, E.A.E. 
2019Synthesis and In Vitro Antitumor Activity of Novel Chromenones Bearing Benzothiazole MoietyDerbala, HA ; El-Shahawi, MM ; Salem MS, ; Ali, MM; Eman A. E. El-Helw 
24-Mar-2025Synthesis of Benzo[h]quinoline derivatives and evaluation of their insecticidal activity against Culex pipiens L. larvaeHosni, Eslam M; E.A.E. El-Helw ; Ramadan, Sayed ; Hashem, Ahmed I.
2020Synthesis of chromenone, pyrimidinone, thiazoline, and quinolone derivatives as prospective antitumor agentsEl-Badawy, AA; Eman A. E. El-Helw 
1-Jan-2024Synthesis, antiproliferative activity, and in silico studies of quinoline-based pyrimidinedione and thiazolidinedione derivativesAlzahrani, Abdullah Y.A.; Ramadan, S.K. ; Eman A. E. El-Helw 
14-Feb-2024Synthesis, computational chemical study, antiproliferative activity screening, and molecular docking of some thiophene-based oxadiazole, triazole, and thiazolidinone derivativesElgubbi, Amna S; Alzahrani, Abdullah Y A; Ramadan, Sayed ; Eman A.E. El-Helw 
2023Synthesis, Cytotoxic, and Antioxidant Activity of Some Benzoquinoline-Based HeterocyclesAsran, Mahmoud; Azab, Mohammad E.; Helal, Maher H.; Sayed K. Ramadan ; Eman A. E. El-Helw 
1-Jan-2023Synthesis, Density Functional Theory, Insecticidal Activity, and Molecular Docking of Some N-Heterocycles Derived from 2-((1,3-Diphenyl-1H-Pyrazol-4-yl)Methylene)Malonyl DiisothiocyanateAbdelrahman, Aya M.; Fahmi, Abdelgawad A.; Rizk, Sameh Ahmed ; Eman A. E. El-Helw 
1-Jan-2023Synthesis, DFT and Antitumor Activity Screening of Some New Heterocycles Derived from 2,2'-(2-(1,3-Diphenyl-1H-Pyrazol-4-yl)Ethene-1,1-Diyl)Bis(4H-Benzo[d][1,3]Oxazin-4-One)Abdelrahman, Aya M.; Fahmi, Abdelgawad A.; Rizk, Sameh Ahmed ; Eman A. E. El-Helw 
Jul-2021Synthesis, DFT, and eco-friendly insecticidal activity of some N-heterocycles derived from 4-((2-oxo-1,2-dihydroquinolin-3-yl)methylene)-2-phenyloxazol-5(4H)-oneGhareeb, Eman A; Mahmoud, Naglaa F H; El-Bordany, Eman A; El-Helw, EAE 
Jan-2025Synthesis, in vivo evaluation, and in silico molecular docking of benzo[h]quinoline derivatives as potential Culex pipiens L. larvicidesHosni, Eslam M; E.A.E. El-Helw ; Ramadan, Sayed K.; Abou-Elmagd, Wael S. I.; Hashem, Ahmed I.
2024Synthesis, insecticidal Activity, and molecular docking analysis of some benzo[h]quinoline derivatives against Culex pipiens L. LarvaeHosni, Eslam M.; Mahmoud Kamal ; Hashem, Ahmed I. ; Sayed Karam Ramadan Emam ; Eman A.E. El-Helw 
2022Ultrasonic Promoted Regioselective Reactions of the Novel Spiro 3,1-Benzoxazon-Isobenzofuranone Dye Toward Some Organic Base ReagentsHassaballah, AI; S.K. Ramadan ; El-Helw, EAE ; Abdelwahab, SS; Rizk, Sameh Ahmed 
6-Jun-2024β-Enaminonitrile in the synthesis of tetrahydrobenzo[b]thiophene candidates with DFT simulation, in vitro antiproliferative assessment, molecular docking, and modeling pharmacokineticsElgubbi, Amna S.; Abousiksaka, Motaleb S.; Alzahrani, Abdullah Y. A.; Sayed Karam Ramadan Emam ; Eman A. E. El-Helw