Browsing by Author Al-Karmalawy, Ahmed A

Showing results 1 to 13 of 13
Issue DateTitleAuthor(s)
2021Concanavalin-A shows synergistic cytotoxicity with tamoxifen via inducing apoptosis in estrogen receptor-positive breast cancer: In vitro and molecular docking studiesElshal, Mohamed; Eid, Norhan; El-Sayed, Ibrahim; El-Sayed, Wael ; Al-Karmalawy, Ahmed A
2025Design and Synthesis of New Multi-Target Coumarin Analogues Acting as Carbonic Anhydrases IX/XII and Topoisomerase II Inhibitors With Apoptotic PotentialAl-Karmalawy, Ahmed A; Yousef, Tarek A; Zeidan, Mohamed A; Sharaky, Marwa; Khatib, Arwa Omar Al; Ferjani, Hela; Abbass, Eslam M; Khalil, A. K. 
2025Design, synthesis, and anticancer evaluation of novel pyrazole--thiophene hybrid derivatives as multitarget inhibitors of wild EGFR, mutant (T790M) EGFR, and VEGFR-2Sallam, Mohammed N; Al-Karmalawy, Ahmed A; Abbass, Eslam M; Hawas, Samia S; El-Naggar, Abeer M; Hassan, A. M. A. 
2025Exploring the potential of some natural indoles as antiviral agents: quantum chemical analysis, inverse molecular docking, and affinity calculationsBelal, Amany; Miski, Samar F; Ghamry, Heba I; Obaidullah, Ahmad J; Zaky, Mohamed Y; Hassan, Ahmed HE; Roh, Eun Joo; Al-Karmalawy, Ahmed A; Ali, Mohamed ; Abdou, Aly
2024Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporterBelal, Amany; Elballal, Mohammed S; Al-Karmalawy, Ahmed A; Hassan, Ahmed HE; Roh, Eun Joo; Ghoneim, Mohammed M; Obaidullah, Ahmad J; Alotaibi, Jawaher M; Shaaban, Salwa; Ali, Mohamed 
2026Multi-target design of fused cyclic pyrimidine-2-thione candidates as DNA intercalators and topoisomerase I/II inhibitorsAl-Karmalawy, Ahmed A; Abo Elmaaty, Ayman; Elsayed, Galal A; Hassan, A. M. A. ; محمود سعيد خليل زكي 
Nov-2025Multi-Target Rational Design and Synthesis of Some 2-Quinolinone Antitumor Candidates Downregulating the Expression of EGFR, VEGFR-2, and Telomerase With Apoptotic PotentialEman A.E. El-Helw ; Mousa, Mai H A; Ghareeb, Eman A; Mahmoud, Naglaa F H; Sharaky, Marwa; El-Bordany, Eman A; Khatib, Arwa Omar Al; Soliman, Elsayed A ; Alnajjar, Radwan; Al-Karmalawy, Ahmed A
2023Novel 4-thiophenyl-pyrazole, pyridine, and pyrimidine derivatives as potential antitumor candidates targeting both EGFR and VEGFR-2; design, synthesis, biological evaluations, and in silico studiesAl-Muntaser, Samia M; Al-Karmalawy, Ahmed A; El-Naggar, Abeer M; Abd El-Sattar, Nour EA; Abbass, Eslam M; Khalil, A. K. 
2024Pharmacophore-based, rationale design, and efficient synthesis of novel tetrahydrobenzo [b] thiophene candidates as potential dual Topo I/II inhibitors and DNA intercalatorsNofal, Hager R ; Al-Karmalawy, Ahmed A; Elmaaty, Ayman Abo; Ismail, Mahmoud F; Abbass, Eslam M; Khalil, A. K. 
2026PTC-Assisted Chemoselective S-Alkylation of 5-Mercapto-1, 3, 4-Oxadiazol Derivative: Multi-Target Anticancer via EGFR, Telomerase, and Thymidylate Synthase Inhibition With Apoptosis InductionZakaria, Asmaa; Al-Karmalawy, Ahmed A; Hawas, Samia S; Elsayed, Galal A; Khatib, Arwa Omar Al; Abbass, Eslam M; Khalil, A. K. 
2024Rational design and eco-friendly one-pot multicomponent synthesis of novel ethylidenehydrazineylthiazol-4 (5H)-ones as potential apoptotic inducers targeting wild and mutant EGFR-TK in triple negative breast cancerAl-Karmalawy, Ahmed A; Sharaky, Marwa; Khattab, Muhammad; Alzahrani, Abdullah Yahya Abdullah; aya ibrahim hassaballah ; Abbass, Eslam M
2024Spirulina versus metformin for controlling some insulin signaling pathway genes in induced polycystic ovary syndrome rat modelEl Leithy, Asmaa A; Abozaid, Mohamed; Al-Karmalawy, Ahmed A; Allam, Rasha Mahmoud; Nourelden, Anas Zakarya; Amer, Rodina M; Abd el Azeem, Nesreen H; Sabra Abo-Zeid, Faten 
2025Ultrastructural effects of Staphylococcus aureus toxicity on albino mice kidneySabra Abo-Zeid, Faten ; Abdurabbah, Ebtisam M; Fares, Nagui H; Al-Karmalawy, Ahmed A