|
| | Issue Date | Title | Author(s) |
| 1 | Aug-2019 | 3D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluation | Sobhy, Mahitab K; Mowafy, Samar; Lasheen, Deena S. ; Farag, Nahla A; Khaled A M Abouzid |
| 2 | 2023 | Annulated pyrazole derivatives as a novel class of urokinase (uPA) inhibitors: Green synthesis, anticancer activity, DNA-damage evaluation, and molecular modelling study | Soliman Farag Saad, Paula ; AboulMagd, Asmaa M; Hemdan, Magdy M. ; Hassaballah, Aya I |
| 3 | Aug-2022 | Conventional and microwave-assisted synthesis, anticancer evaluation, 99mTc-coupling and In-vivo study of some novel pyrazolone derivatives | Essa, Basma M; Selim, Adli A; Sayed, Galal H; Kurls Ekram Anwer |
| 4 | Oct-2021 | Design and synthesis of novel 4-fluorobenzamide-based derivatives as promising anti-inflammatory and analgesic agents with an enhanced gastric tolerability and COX-inhibitory activity | Halim, Peter A; Georgey, Hanan H; George, Mina Y. ; El Kerdawy, Ahmed M; Said, Mona F |
| 5 | 2020 | Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers. | Eslam M. Abbass; Ali Kh. Khalil; Mohamed M. Mohamed; Ibrahim H. Eissa; El- naggar, Abeer |
| 6 | 2021 | Design, microwave assisted synthesis, and molecular modeling study of some new 1, 3, 4-thiadiazole derivatives as potent anticancer agents and potential VEGFR-2 inhibitors | Paula S. Farag ; AboulMagd, Asmaa M; Farag, Paula S |
| 7 | Dec-2019 | Design, Molecular Modeling and Anticancer Evaluation of Thieno[2,3-d]pyrimidine Derivatives as Inhibitors of Topoisomerase II | El-Sayed, Wael ; El-Metwally SA; Khalil A |
| 8 | Oct-2014 | Design, synthesis and biological evaluation of type-II VEGFR-2 inhibitors based on quinoxaline scaffold | Abou El Ella, Dalal ; Ismail, Nasser S M; Abouzid, Khaled ; Shahin, Mai I. |
| 9 | Dec-2014 | Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents | Abdel-Atty, Mona M; Farag, Nahla A; Kassab, Shaymaa E; Serya, Rabah ; Khaled A M Abouzid |
| 10 | 202 | Design, synthesis, and SAR studies of novel 4-methoxyphenyl pyrazole and pyrimidine derivatives as potential dual tyrosine kinase inhibitors targeting both EGFR and VEGFR-2. | El- naggar, Abeer ; A.M.A. Hassan; Eslam B. Elkaeed; Mohamed S. Alesawy; Ahmed A. Al-Karmalawy |
| 11 | 2019 | Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors. | Lamia H.T. Amina; Taghreed Z. Shawera; El- naggar, Abeer ; Hend M.A. El-Sehrawi |
| 12 | 2019 | Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activity | Elsayed, Nevine M Y; Serya, Rabah ; Tolba, Mai ; Ahmed, Marawan; Barakat, Khaled; Abou El Ella, Dalal ; Khaled A M Abouzid |
| 13 | Jun-2015 | Discovery of novel tricyclic pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amine derivatives as VEGFR-2 inhibitors | Abdel Aziz, Yasmine M; Said, Mohamed M; El Shihawy, Hosam A; Abouzid, Khaled |
| 14 | Aug-2021 | Discovery of potent thieno[2,3-d]pyrimidine VEGFR-2 inhibitors: Design, synthesis and enzyme inhibitory evaluation supported by molecular dynamics simulations | Elrazaz, Eman ; Serya, Rabah A T; Ismail, Nasser S M; Albohy, Amgad; Abou El Ella, Dalal ; Khaled A M Abouzid |
| 15 | 2021 | Eco-friendly sequential one-pot synthesis, molecular docking, and anticancer evaluation of arylidene-hydrazinyl-thiazole derivatives as CDK2 inhibitors. | El- naggar, Abeer ; Maher A. El-Hashash; Eslam B. Elkaeed |
| 16 | Apr-2023 | Exploring the cytotoxic effect and CDK-9 inhibition potential of novel sulfaguanidine-based azopyrazolidine-3,5-diones and 3,5-diaminoazopyrazoles | Husseiny, Ebtehal M; S Abulkhair, Hamada; El-Dydamony, Nehad M; Kurls Ekram Anwer |
| 17 | Dec-2018 | Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling | Adel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid |
| 18 | 2018 | Imidazo[2',1':2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study | Ewida, Menna A; Abou El Ella, Dalal ; Lasheen, Deena S. ; Ewida, Heba A; El-Gazzar, Yomna I; El-Subbagh, Hussein I |
| 19 | 1-Dec-2021 | Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancer | Dokla, Eman ; Abdel-Aziz, Amal Kamal; Milik, Sandra N.; Mahmoud, Amr H.; Saadeldin, Mona Kamal; McPhillie, Martin J.; Minucci, Saverio; Khaled A M Abouzid |
| 20 | Jun-2014 | Molecular design and synthesis of 1,4-disubstituted piperazines as α(1)-adrenergic receptor blockers | Hussein, Mohammed M; Serya, Rabah ; Abdel Naby, Rana M; Al-Abd, Ahmed M; Saleh, Dalia O; El-Eraky, Wafaa I; Khaled A M Abouzid ; Abou El Ella, Dalal |
