Hekal, Mohamed H.

mohamed.hekal@sci.asu.edu.eg
Interests: Synthetic organic chemistry, Design and synthesis of molecules having unique biological activity, In vitro anticancer evaluation,
Internal ID: rp11457
  • 169 Scopus Citations
  • 2 PubMed Citations
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mohamed.hekal@sci.asu.edu.eg
 
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Hekal, Mohamed H.
 
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Publications

Results 1-20 of 35 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
129-Apr-2026New benzochromene-based compounds as potential EGFR-TK inhibitors: synthesis, anti-proliferative activity, molecular docking studies, and ADME profilesAbdullah Alzahrani, Abdullah Yahya; Alrashdi, Saad; Abu El-Azm, Fatma S M; Ali, Yasmeen M; Hekal, Mohamed H. 
22026Transformation of 3-(4-methoxybenzylidine)-5-(p-tolyl)-2(3H)-furanone into new nitrogen heterocyclic candidates as insecticidal agents with in silico studiesGad, Nourhan M.; Haneen, David S. A. ; Hosni, Eslam M.; Hekal, Mohamed H. ; Abdalha, Abdelaal A.; Sayed Karam Ramadan Emam ; Wael Abou-Elmagd 
32026New Pyrazole-Based Compounds as Potential Multi-Kinase Inhibitors with Antiproliferative Activity: Synthesis, In Vitro Biological Evaluation, and In Silico StudiesSamir, Sandy S; Abdel-Megid, Mohamed; Salem, Mostafa E; Hekal, Mohamed H. ; Ali, Yasmeen M; Alzahrani, Abdullah YA; Rafat, El-Hady; samy samir, sandy 
431-Jul-2025Synthesis and in silico studies of new thiophene-isoquinolinone hybrids as potential larvicides against Culex pipiensMohamed Abo Elhoda Darwish ; Hekal, Mohamed H. ; El-Azm, Fatma S. M. Abu ; Hosni, Eslam M; Ali, Yasmeen M; Yahya Abdullah Alzahrani, Abdullah; Rafat, El-Hady
52025Synthesis, SAR, and in silico studies of new benzochromene derivatives as insecticidal agents against Culex pipiens L. larvae and adultsGhonim, Hossam; Abou-Elmagd, Wael SI; Khalil, Eid M; Abdalha, Abdelaal A; Samir, Sandy S; Doaa Ramadan Abdel Haleem Ramadan ; Hekal, Mohamed H ; Wael Abou-Elmagd ; samy samir, sandy 
62025Synthesis, biological evaluation, and in silico studies of new pyrrolone derivatives as potent antiproliferative agentsHekal, Mohamed H. ; El-Azm, Fatma SM Abu; Samir, Sandy S; Alzahrani, Abdullah YA; Ali, Yasmeen M; samy samir, sandy 
718-Oct-2024Rational design and synthesis of new pyrrolone candidates as prospective insecticidal agents against Culex pipiens L. LarvaeHekal, Mohamed H. ; Abdel-Haleem, Doaa R; Rafat, El-Hady; Ali, Yasmeen M; Hashem, Ahmed ; Abu El-Azm, Fatma 
817-Jul-2024Synthesis, DFT Calculations, and Biological Studies of New 2-cyano-3-(naphthalene-1-yl)acryloyl amide Analogues as Anticancer AgentsHekal, Mohamed H. ; Abdalha, Abdelaal A; Farag, Hanaa; Mohamed, Amira T A; Abu El-Azm, Fatma 
93-Jan-2024New pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors: design, green synthesis, potential anti-proliferative activity and P-glycoprotein inhibitionHassaballah, Aya I; AboulMagd, Asmaa M; Hemdan, Magdy M. ; Hekal, Mohamed H. ; El-Sayed, Amira A; Farag, Paula S; Aya I. Hassaballah, hassaballah, Aya I. ; Abu El-Azm, Fatma 
101-Jan-2024Novel pyrano[2,3-c]pyrazolopyrimidines as promising anticancer agents: Design, synthesis, and cell cycle arrest of HepG2 cells at S phaseHaneen, David S.A. ; Hekal, Mohamed H. ; El-Sayed, Wael ; Wael Abou-Elmagd ; Abu El-Azm, Fatma 
112024Publisher Correction: Rational design and synthesis of new pyrrolone candidates as prospective insecticidal agents against Culex pipiens L. LarvaeEl-Azm, Fatma SM Abu; Rafat, El-Hady; Ali, Yasmeen M; Hashem, Ahmed ; Hekal, Mohamed H ; Doaa Ramadan Abdel Haleem Ramadan ; Abu El-Azm, Fatma 
122023New 1, 3, 4-thiadiazoles as potential anticancer agents: pro-apoptotic, cell cycle arrest, molecular modelling, and ADMET profileHekal, Mohamed H ; Soliman Farag Saad, Paula ; Hemdan, Magdy M. ; El-Sayed, Amira A; Hassaballah, Aya I; El-Sayed, Wael ; Aya I. Hassaballah, hassaballah, Aya I. 
132023Diversity oriented synthesis and SAR studies of new quinazolinones and related compounds as insecticidal agents against Culex pipiens L. Larvae and associated predatorAli, Yasmeen M; El-Azm, Fatma SM Abu; Doaa Ramadan Abdel Haleem Ramadan ; Hekal, Mohamed H ; Abu El-Azm, Fatma 
142-Aug-2021An efficient synthesis and evaluation of some novel quinazolinone-pyrazole hybrids as potential antiproliferative agentsAbdelaal A. Abdalha ; Mohamed Hussein Hussein Moustafa Hekal ; Abu El-Azm, Fatma 
1516-Jul-2021New N-(1,3,4-thiadiazol-2-yl)furan-2-carboxamide derivatives as potential inhibitors of the VEGFR-2Soliman Farag Saad, Paula ; Hemdan, Magdy M. ; El-Sayed, Wael ; Mohamed Hussein Hussein Moustafa Hekal 
162021An efficient approach for the synthesis and antimicrobial evaluation of some new benzocoumarins and related compoundsMohamed Hussein Hussein Moustafa Hekal ; Abu El-Azm, Fatma ; Samir, SS; samy samir, sandy 
172021New Benzochromeno[2,3-d]Pyrimidines and Benzochromenotriazolo[1,5-c]Pyrimidines as Potential Inhibitors of Topoisomerase IISamir, SS; Ali, YM; El-Sayed, Wael ; Hekal, Mohamed H. 
18Jun-2020Synthesis of new oxadiazol-phthalazin derivatives with anti-proliferative activity; molecular docking, pro-Apoptotic, and enzyme inhibition profileEl-Sayed, Wael ; El-Naggar AM; Abu El-Azm, Fatma ; Mohamed Hekal 
192020Utilization of cyanoacetohydrazide and 2-(1,3-dioxoisoindolin-2-yl) acetyl chloride in the synthesis of some novel anti-proliferative heterocyclic compoundsMohamed Hekal ; Ali, Yasmeen M.; Abu El-Azm, Fatma 
2019-Oct-2019Convenient synthesis and anti-proliferative activity of some benzochromenes and chromenotriazolopyrimidines under classical methods and phase transfer catalysisAmira T. Ali; Mohamed Hekal