Abouzid, Khaled

khaled.abouzid@pharma.asu.edu.eg

Department of Pharmaceutical Chemistry - Pharmacy
Interests: Anticancer drug discovery, design and synthesis, Antimicrobial,
Internal ID: rp12178
  • 3,121 Scopus Citations
  • 592 PubMed Citations

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Full Name
Abouzid, Khaled
 
 
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Biography
Dr. Khaled Abouzid is a Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Prominent Scholar in Drug Discovery, Co-founding Director of Center of Drug Discovery and Development Research ASU He was nominated as the Acting Dean of the Faculty of Pharmacy, University of Sadat City from 8-2018 to 8-2022. He is currently a member of national pharmaceutical chemistry promotion committee
Dr. Abouzid’s research is directed towards drug discovery of bioactive small molecules with special emphasis on cannabinoids, targeted anticancer, anti-inflammatory, anti-viral anti-microbial agents and enzyme inhibitors. He has published over 150 research papers, two books and filed 14 patents in medicinal chemistry. He has Scopus H index of 28. He has supervised over 100 Master and PhD students in 7 universities. Dr Abouzid has research collaborations with German, British, Swedish, Canadian and US universities. He has also organized and presided over 34 international symposia and conferences.
Dr. Abouzid obtained his B.Sc. degree in Pharmaceutical Sciences from Cairo University in 1985, and his PhD. joint degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University and School of Pharmacy University of Connecticut, USA.
Dr. Abouzid started his career in 1995 as a lecturer of Organic Chemistry at Cairo University, Faculty of Pharmacy. In 2001, he moved to the Department of Pharmaceutical Chemistry, Ain Shams University, and was promoted to Associate Professor in 2003. He did postdoctoral work with Professor Jochen Lehman of the Friedrich-Schiller-Universität Jena, Germany.

Publications

Results 61-80 of 134 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
612015Targeting apoptotic machinery as approach for anticancer therapy: Smac mimetics as anticancer agentsElsayed, NMY; Abou El Ella, D.A. ; Serya, RAT; Abouzid, Khaled 
622015Synthesis and in vitro antiproliferative activity of novel pyrazolo[3,4-d]pyrimidine derivativesAbdou, Nermin S.; Serya, Rabah ; Esmat, Ahmed ; Tolba, Mai F.; Ismail, Nasser S. M.; Khaled A M Abouzid 
632015Design, synthesis and biological evaluation of Novel Curcumin Analogs with anticipated anticancer activityFawzy, IM; Youssef, KM; Ismail, NSM; Gullbo, J; Abouzid, Khaled 
642015Discovery of Potent Antiproliferative Agents Targeting EGFR Tyrosine Kinase Based on the Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amine ScaffoldAziz, Yasmine Mohamed Abdel; Said, Mohamed Mokhtar; El Shihawy, Hosam Ahmed; Tolba, Mai ; Abouzid, Khaled 
65Jun-2015Discovery of novel tricyclic pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amine derivatives as VEGFR-2 inhibitorsAbdel Aziz, Yasmine M; Said, Mohamed M; El Shihawy, Hosam A; Abouzid, Khaled 
66Nov-2015Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) ActivatorsFang, Chun-Sheng; Lai, Po-Ting; Kulp, Samuel K; Serya, Rabah ; Ismail, Nasser S M; Chen, Ching-Shih; Dokla, Eman ; Khaled A M Abouzid 
67Dec-2015Discovery of Novel Peptidomimetics as Irreversible CHIKV NsP2 Protease Inhibitors Using Quantum Mechanical-Based Ligand DescriptorsEl-labbad, Eman M; Ismail, Mohammed A H; Abou Ei Ella, Dalal A; Ahmed, Marawan; Wang, Feng; Barakat, Khaled H; Abouzid, Khaled 
682016Design, synthesis and biological evaluation of indazole–pyrimidine based derivatives as anticancer agents with anti-angiogenic and antiproliferative activitiesElsayed, Nevine M. Y.; Abou El Ella, Dalal ; Serya, Rabah A. T.; Tolba, Mai F.; Shalaby, Raed; Khaled A M Abouzid 
692016Furo[2,3-d]pyrimidine based derivatives as kinase inhibitors and anticancer agentsAziz, M.A. ; Serya, RAT; Lasheen, DS; Abouzid, Khaled 
7015-Apr-2016Discovery of Potent VEGFR-2 Inhibitors based on Furopyrimidine and Thienopyrimidne Scaffolds as Cancer Targeting AgentsAziz, Marwa A; Serya, Rabah A T; Lasheen, Deena S. ; Abdel-Aziz, Amal Kamal ; Mansour, Ahmed M; Ahmed Esmat ; Singab A. ; Khaled A M Abouzid 
71May-2016Quinoxaline-Based Scaffolds Targeting Tyrosine Kinases and Their Potential Anticancer ActivityEl Newahie, Aliya M S; Ismail, Nasser S M; Abou El Ella, Dalal ; Abouzid, Khaled 
72Aug-2016Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical ProfilesHossam, Monia; Lasheen, Deena S. ; Abouzid, Khaled 
7315-Aug-2016Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivativesMowafy, Samar; Galanis, A; Doctor, Zainab M; Paranal, Raymond M; Lasheen, Deena S. ; Farag, Nahla A; Jänne, Pasi A; Abouzid, Khaled 
7421-Oct-2016Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionalityOsman, Noha A; Ligresti, Alessia; Klein, Christian D; Allarà, Marco; Rabbito, Alessandro; Di Marzo, Vincenzo; Abouzid, Khaled ; Abadi, Ashraf H
75Nov-2016Design and Synthesis of 4-Anilinothieno[2,3-d]pyrimidine-Based Compounds as Dual EGFR/HER-2 InhibitorsAbd El Hadi, Soha R; Lasheen, Deena S. ; Hassan, Mahmoud A; Khaled A M Abouzid 
7630-Jan-2017Click and Release: SO2 Prodrugs with Tunable Release RatesSerya, Rabah ; Khaled A.M.abouzid; Deena S.Lasheen; Xingyue Ji; Binghe Wang; Khaled A M Abouzid 
77Mar-2017Pyridazine Based Scaffolds as Privileged Structures in anti-Cancer TherapyJaballah, Maiy Youssef; Serya, Rabah Taha; Abouzid, Khaled 
786-Jul-2017Synthesis, ADMET Properties, and Biological Evaluation of Benzothiazole Compounds Targeting Chemokine Receptor 2 (CXCR2)Mehanna, Wesam E; Lu, Tiangong; Debnath, Bikash; Lasheen, Deena S. ; Serya, Rabah A T; Abouzid, Khaled ; Neamati, Nouri
797-Jul-2017Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activitiesAbouzid, Khaled ; Al-Ansary, Ghada H; El- naggar, Abeer 
80Nov-2017Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer ActivitiesGhith, Amna; Ismail, Nasser S M; Youssef, Khairia; Abouzid, Khaled