SOLUBLE INTERLEUKIN-2 RECEPTOR AS A MARKER OF T CELL ACTIVATION IN BRONCHIAL ASTHMA
Gehan Sabry Asaad Yousef;
Abstract
Over the past decade, asthma has been defined as a
disease that is principally inflammatory in nature, even in individuals with mild clinical disease. The pathologic hallmark of ongoing asthma is the presence of a submucosal infiltrate of inflammatory cells.
The study was designed to determine the degree of activation of T lymphocytes of patients with asthma by measuring the concentration of soluble interleukin-2 receptor in the serum from asthma patients with acute attacks and in renusswn.
We examined 30 asthmatic children in their wheezy state and 30 asthmatic children during remission as well as 20 healthy children matching age and sex. The patients and controls were subjected to full history taking, complete clinical examination, and complete blood picture (including total leucocytic count, Hb% and absolute eosinophilic count) chest X-ray and serum soluble interleukin-2 receptors.
Statistical analysis of the results showed highly significant difference in serum siL-2R from patients with acute
disease that is principally inflammatory in nature, even in individuals with mild clinical disease. The pathologic hallmark of ongoing asthma is the presence of a submucosal infiltrate of inflammatory cells.
The study was designed to determine the degree of activation of T lymphocytes of patients with asthma by measuring the concentration of soluble interleukin-2 receptor in the serum from asthma patients with acute attacks and in renusswn.
We examined 30 asthmatic children in their wheezy state and 30 asthmatic children during remission as well as 20 healthy children matching age and sex. The patients and controls were subjected to full history taking, complete clinical examination, and complete blood picture (including total leucocytic count, Hb% and absolute eosinophilic count) chest X-ray and serum soluble interleukin-2 receptors.
Statistical analysis of the results showed highly significant difference in serum siL-2R from patients with acute
Other data
| Title | SOLUBLE INTERLEUKIN-2 RECEPTOR AS A MARKER OF T CELL ACTIVATION IN BRONCHIAL ASTHMA | Other Titles | مستقبلات انترليوكين-2 المذابة كعلامة لنشاط خليه تي- في مرض الربو الشعبي | Authors | Gehan Sabry Asaad Yousef | Issue Date | 2002 |
Attached Files
| File | Size | Format | |
|---|---|---|---|
| Gehan Sabry Asaad Yousef.pdf | 2.34 MB | Adobe PDF | View/Open |
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