Study of Neutrophil gelatinase-associated Lipocalin in non septic patients with risk of Acute Kidney Injury in ICU.
Islam Sobhy Abd El Fattah;
Abstract
Our study included 50 patients admitted togeneral ICUs of Nasser Institute Hospital.
Patient was followed for 1st 2 weeks of ICU admission and divided into 2 equal groups:
• Group A: 25 patients who developed AKI with estimation of serum NGAL twice:
Within 24 hour of admission.
At time of AKI development (stage 1) only.
• Group B: 25 patients who did not develop AKI.
Our study showed highly significance correlation between Serum NGAL as a marker of AKI at time of admission and after development of AKI.
The present study Showed that NGAL as highly predictor of AKI with highly specificity (96%) and sensitivity (72%).
The present studyShowed NGAL as a predictor of hemodialysis with specificity (71.4%) and sensitivity (63.6%).
The present studyShowed NGAL as a predictor of patient's outcome with specificity (68%) and sensitivity (50%).
The present study showed significant correlation between Serum NGAL as a marker of AKI and Hgb at time of AKI.
And no significance correlation between Serum NGAL as a marker of AKI and other laboratory data.
As conclusionswe support the use of NGAL as a biomarker for the prediction of AKI with highly specificity in aseptic patients in ICU.
Patient was followed for 1st 2 weeks of ICU admission and divided into 2 equal groups:
• Group A: 25 patients who developed AKI with estimation of serum NGAL twice:
Within 24 hour of admission.
At time of AKI development (stage 1) only.
• Group B: 25 patients who did not develop AKI.
Our study showed highly significance correlation between Serum NGAL as a marker of AKI at time of admission and after development of AKI.
The present study Showed that NGAL as highly predictor of AKI with highly specificity (96%) and sensitivity (72%).
The present studyShowed NGAL as a predictor of hemodialysis with specificity (71.4%) and sensitivity (63.6%).
The present studyShowed NGAL as a predictor of patient's outcome with specificity (68%) and sensitivity (50%).
The present study showed significant correlation between Serum NGAL as a marker of AKI and Hgb at time of AKI.
And no significance correlation between Serum NGAL as a marker of AKI and other laboratory data.
As conclusionswe support the use of NGAL as a biomarker for the prediction of AKI with highly specificity in aseptic patients in ICU.
Other data
| Title | Study of Neutrophil gelatinase-associated Lipocalin in non septic patients with risk of Acute Kidney Injury in ICU. | Other Titles | دراسة الدلالة البيولوجية للكلى مادة الليبوكالين المصاحبة لانزيم الجيلاتينيز في مرضى وحدة الرعاية المركزة بدون تسمم بالدم مع خطورة حدوث فشل كلوي حاد | Authors | Islam Sobhy Abd El Fattah | Issue Date | 2015 |
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