The Relation between Serum Ascorbic Acid Concentration and Preterm Premature Rupture of Membranes
Karim Mohamed Ezz El Din Mohamed;
Abstract
SUMMARY
P
remature rupture of membrane (PROM) is defined as rupture of membranes before the onset of labor, while rupture of fetal membranes before 37 weeks gestation is defined as preterm premature rupture of membranes (PPROM). It is a problem that complicates approximately 10 % of all pregnancies. PROM is usually associated with significant perinatal and maternal morbidities.
Role of vitamin c in the integrity of fetal membranes was studied due to its well described role in the biosynthesis of collagen, the main structural constituent of chorioamnotic membrane.
Vitamin C reaches the avascular fetal membranes through the maternal circulation to the decidual side.
Vitamin C deficiency during pregnancy could lead to PROM by affecting collagen metabolism and its deposits in fetal tissues, including the chorioamnotic membranes.
It has been suggested that maintaining adequate vitamin C status could help to reduce incidence of PROM.
This case-control study was conducted to evaluate the relation between vitamin c and PPROM during the period from January 2016 and November 2016. 60 pregn
P
remature rupture of membrane (PROM) is defined as rupture of membranes before the onset of labor, while rupture of fetal membranes before 37 weeks gestation is defined as preterm premature rupture of membranes (PPROM). It is a problem that complicates approximately 10 % of all pregnancies. PROM is usually associated with significant perinatal and maternal morbidities.
Role of vitamin c in the integrity of fetal membranes was studied due to its well described role in the biosynthesis of collagen, the main structural constituent of chorioamnotic membrane.
Vitamin C reaches the avascular fetal membranes through the maternal circulation to the decidual side.
Vitamin C deficiency during pregnancy could lead to PROM by affecting collagen metabolism and its deposits in fetal tissues, including the chorioamnotic membranes.
It has been suggested that maintaining adequate vitamin C status could help to reduce incidence of PROM.
This case-control study was conducted to evaluate the relation between vitamin c and PPROM during the period from January 2016 and November 2016. 60 pregn
Other data
| Title | The Relation between Serum Ascorbic Acid Concentration and Preterm Premature Rupture of Membranes | Other Titles | العلاقة بين تركيز حمض الاسكوربيك بالدم والتمزق المبكر للاغشية حول الجنين | Authors | Karim Mohamed Ezz El Din Mohamed | Issue Date | 2017 |
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