The Relation Between Neutrophil /Lymphocyte Ratio and Atherosclerotic Coronary Artery Disease Detected by Multislice Computed Tomography in Type Two Diabetic Patients

Abstract

oronary artery disease (CAD) is one of the most common causes of mortality worldwide. In Egypt prevalence of CAD is more than 8%. Diabetes is one of the important risk factors of atherosclerosis. Recent evidence has demonstrated an important role of inflammation in atherosclerosis. Atherosclerosis is an active process rather than passive accumulation of lipid in the vascular lumen. Neutrophil- to- Lymphocyte ratio (NLR) is an emerging biomarker of inflammation. It is cheap and easily calculated from the neutrophil and lymphocyte count obtained from the complete blood count with differentials. The aim of our study is to investigate the relation between NLR and atherosclerotic CAD in type 2 diabetes mellitus (T2DM) patients using multisclice computed tomography (MSCT). Our study was conducted upon 60 T2DM patients presented to Ain Shams and Misr University hospitals and were referred to do MSCT for assessment of CAD. All patients were subjected to full history taking including risk factor for CAD as diabetes mellitus, hypertension, dyslipidemia, smoking and family history of