Effect ¬¬¬¬¬of Endometrial Injury before Frozen Embryo Transfer on Pregnancy Rate (Randomized Controlled Trial

Abstract

The objective of this randomized controlled trial was to assess the efficacy ¬¬¬¬¬of endometrial injury before Frozen –thawed embryo transfer on pregnancy rate in women aged below 42 years undergoing frozen embryo transfer. An endometrial injury could produce local inflammatory reactions and angiogenic environment between the endometrium and the conceptus which, in turn, facilitates embryo implantation and subsequent pregnancy in earlier studies. The study was conducted at the ART unit of Ain Shams University Maternity Hospital and Dar el Teb Fertility center during the period from March 2017 to October 2017. This randomized study consisted of 50 patients were prepared to do Frozen-thawed embryo transfer and designed as the following 2 groups: Group (A): consists of 25 patients received frozen embryo with single induced injury was done on the posterior endometrium on day 7 of the transfer cycle by using modified Cook catheter. Group (B): consists of 25 patients received frozen embryo without endometrial scratching as control group