“Erosive Effect Of Aspirin On Primary Teeth Enamel In Children With Heart Disease: In vivo and In vitro study”

Abstract

The enamel of primary teeth is less mineralized than that of permanent teeth and the density of its outermost layer is lesser. So it is more susceptible to erosion than permanent teeth enamel. Erosion in primary teeth may be associated with dental hypersensitivity, loss of the occlusal vertical dimension, eating difficulties, poor esthetics, pulp exposure, and abscesses. Children with heart disease requires special attention, because of their heightened susceptibility to infectious endocarditis, associated with bacteremia induced by invasive dental procedures. Furthermore, these patients commonly have developmental enamel defects that increase their susceptibility to dental erosion, and often have poor oral health. The latter condition may be largely attributed to cardiac disease, whose attention and care may cause oral health to be underestimated and not be given due importance. In addition, the chronic administration of medicines sweetened with sucrose and acidic drugs such as aspirin may increase the incidence of caries and gingivitis in children. Accordingly, the aim of the present study was evaluation of the erosive effect of aspirin on primary teeth enamel in children with heart diseases, and to determine the proper route of administration to control that erosive effect. This study was divided into two parts, in vivo and in vitro part, In vivo part