Relationship Between Serum Hemojuvelin And Iron Requirement In Chronic Hepatitis C In Hemodialysis Patients

Abstract

Iron deficiency anemia is an important problem commonly associated with patients on maintenance hemodialysis (MHD). Hepcidin plays an important role in the regulation of iron metabolism (Ganz, 2011). HJV was demonstrated to be crucial for its role in regulating hepcidin expression (Babitt et al., 2006). HJV was found to be elevated in hemodialysis (HD) patients and correlated to kidney function and iron status. It appears that HJV could be a new player in the iron metabolism in HD patients (Malyszko (A) et al., 2012). We aimed in our study to evaluate the level of hemojuvelin in hemodialysis patients, identify the association of hemojuvelin level with iron parameters in hemodialysis patients and to compare hemojuvelin level in hepatitis c virus positive hemodialysis patients to those who are hepatitis c virus negative.