Synthesis, spectroscopic and thermal studies for ternary glutamate and other amino acids of divalent metal complexes and their effect on the metal weight loss inhibition.

Abstract

(Ternary complexes of Ni(II), Co (II), Cu(II), and Zn(II) with glutamic acid as a primary ligand and Nitrilotriacetic acid [HNTA2- ] or alanine as a secondary ligand were syn-thesized in slightly acidic medium. Characterization of the new com¬plexes were performed by elemental analysis, Fou-rier transform infrared, UV–Visible spectrophotometr, thermal analysis, magnetic measurements and mass spec-troscopy. The complexes have been suggested to show ge-ometry of an octahedral symmetry .The results indicated that the ternary complexes were isolated in 1:1:1 (M: glu-tamic: HNTA ) ratios, and the molecular structures were suggested to Be [M(glutamic)(HNTA)(H2O)].(2-1.5)H2O and [M(glutamic)(alanine)(H2O)2].(1-0.5)H2O.The prepared complexes were used in weight loss studies of aluminim and copper plates , antimicrobial activities of the prepared complexes against Escherichia coli, Staphylococcus aureus ,Candida albicans and Aspergillus flavus were in-vestigated and evaluated for their in vitro anticancer activ-ity against hepatocellular carcinoma .