Serum Insulin, C.Peptide And Serum Pro-Insulin In Pre And Post Renal Transplantation

Fady Magdy Gamil Fahmy;

Abstract


ew onset of diabetes mellitus (NODAT) after renal transplantation is one of the common complications that is increasingly occurring among kidney transplanted recipients.
The risk of (NODAT) or also called post-transplant diabetes mellitus (PTDM) increase with the time of transplantation,the incidence of NODAT ranges from approximately 2% to 25% with current immunosuppressive regimens,but rates as high as 46% were reported with earlier more diabetogenic regimens therefore early detection and prompt action are essential in reducing the risk of NODAT and its complications.
Risk factors of PTDM are modifiable and unmodifiable risk factors,unmodifiable includes age,ethinicity,hereditary and family history of diabetes,modifiable risk factor include obesity, immunosuppressive drugs,transplant rejection,HCV and CMV infections.
Any factor that increase the systemic inflammatory state in the cours of the transplantation is associated with increase risk of PTDM.
Immunosuppressive medications used in renal transplantation can be classified to induction agents, maintenance therapy and treatment of rejection.


Other data

Title Serum Insulin, C.Peptide And Serum Pro-Insulin In Pre And Post Renal Transplantation
Authors Fady Magdy Gamil Fahmy
Issue Date 2018

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