Impact of CMV Viremia on Allogeneic Peripheral Blood Stem Cell Transplantation in Patients with Acute Leukemia
Gehad Adel Mohammed Hasan;
Abstract
llogeneic hematopoietic stem cell transplantation (Allo-HSCT) is the only curative treatment for acute leukemia patients.
Despite progress in immunosuppressive and antiviral therapy, acute graft-versus-host disease (aGVHD) and cytomegalovirus (CMV) infection remain important complications after allogeneic HSCT. GVHD and CMV replication are pathogenetically associated: multiple studies show that GVHD and its treatment put patients at risk for CMV replication. In contrast, the role of CMV replication as a cause of GVHD is controversial.
Despite progress in immunosuppressive and antiviral therapy, acute graft-versus-host disease (aGVHD) and cytomegalovirus (CMV) infection remain important complications after allogeneic HSCT. GVHD and CMV replication are pathogenetically associated: multiple studies show that GVHD and its treatment put patients at risk for CMV replication. In contrast, the role of CMV replication as a cause of GVHD is controversial.
Other data
| Title | Impact of CMV Viremia on Allogeneic Peripheral Blood Stem Cell Transplantation in Patients with Acute Leukemia | Other Titles | تأثير الإصابة بالسيتوميجالو فيروس في المرضى الذين يعانون من اللوكيميا الحادة بعد عملية زرع الخلايا الجذعية الطرفية من متبرع | Authors | Gehad Adel Mohammed Hasan | Issue Date | 2018 |
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