Comparison between L-FABP and Renal Artery Duplex before & after Percutaneous Coronary Intervention for Early Detection of Acute Kidney Injury

Abstract

Patient assessment by imaging studies using contrast media is currently replacing open procedures, especially in high-risk patients. However, the use of such contrast media might result in acute events and injuries after the procedure such as acute kidney injury (AKI). So we conducted a prospective study on 40 patients admitted to the ICU Critical Care Department, Cairo University Hospitals scheduled for coronary angiography to assess the clinical biomarker Liver Fatty acid binding protein (L-FABP) and the renal resistive index (RRI) by renal artery duplex for early prediction of acute kidney injury. L-FABP was done for all candidate patients before and 4 h after angiography. Renal Doppler was done before and after angiography. RIFLE (Risk, Injury, Failure, Loss and end stage renal disease) criteria were used to assess the acute kidney injury.