Assessment of Uterine Cervical Cancer by Means of MR Spectroscopy

Abstract

roton magnetic resonance spectroscopy has been shown to have clinical value in managing cancers of the brain, breast, cervix and prostate, it is useful for diagnosing and monitoring treatment of cervical cancer by analyzing the metabolites composition of cervical tumors, providing details of tumors metabolism that might assist tumor grading and leading to a better understanding of the biochemical pathways found within the lesion, serving as a noninvasive biomarker of metabolism in tumors. Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinical use. 1H-MRS has achieved great strides as a molecular imaging technique since its introduction, and its scope in many clinical scenarios and research settings is rising. 1H-MRS technique can aid in the management of cancer patients, serving as a noninvasive biomarker of metabolism in tumors.