The Effect of Bone Marrow Aspirate Concentrate on Bone Regenerate During Rapid Mandibular Distraction Osteogensis

Abstract

Bone reconstruction procedures in the craniofacial region are considered a complicated condition, which usually require skeletal correction to overcome psychological, breathing and eating problems by reconstructing both soft and hard tissues. Grafting from distant sites to regenerate and reconstruct missing bony segments carries the risk of donor site morbidity, the risk of rejection, infection or low bone quality. Distraction osteogenesis (DO) is a surgical process used in reconstruction of skeletal deformities and lengthening of the long bones. Distraction technology was used mainly in orthopedics and is currently used in the oral and maxillofacial region to correct deformities of the facial skeleton without grafting risk (1). Distraction osteogenesis refers to a surgical technique designed to address defects and deficiencies in the skeleton. Distraction osteogenesis originally was first mentioned by Hippocrates; Ilizarov introduced the DO 40 years ago and the orthopedic community has employed distraction techniques to lengthen and reconstruct arms and legs (2)