Diabetic Retinopathy Vascular Density Maps Using Optical Coherence Topograghy Angiograghy

Abstract

iabetic retinopathy (DR) is one of the most common diabetic complications, which has become a leading cause for vision loss, mainly because of macular edema and vitreous hemorrhage. From 1990–2010, DR ranked as the fifth most common cause of preventable blindness and fifth most common cause of moderate to severe visual impairment. In 2010, of an estimated 285 million people worldwide with diabetes, over one-third have signs of DR, and a third of these are afflicted with vision-threatening diabetic retinopathy (VTDR), defined as severe non-proliferative DR or proliferative DR (PDR) or the presence of diabetic macular edema (DME). OCT angiography (OCT-A), a dye-free imaging technique useful to visualize retinal and choroidal vasculature, has allowed to detect angiographic features of DR and changes in the macular capillary network, even before disease onset. In patients with DR, areas of nonperfusion and their localization in the superficial and deep plexuses, irregular capillaries and micro aneurysms have been clearly analyzed. We conducted our study to use Optical Coherence Tomography(OCT) and Optical Coherence Tomography Angiography (OCT-A) for qualitative and quantitative