EVALUATION OF THE ROLE OF QUANTITATIVE CORONARY ANGIOGRAPHY lN ESTIMATlNG THE PERCNTAGE DIAMETER STENOSIS: A COMPARATIVE STUDY BETWEEN QCA, IVUS

Abstract

Objectives: Assessment of accuracy of quantitative coronary angiography m evaluation of

intermediate coronary lesions compared to IVUS as the golden standard. Background: Coronary arteriographY is considered the standard method in diagnosing CAD. However it has many limitations, intravascular ultrasound with its new insights in tomographic• imaging of coronary arterial wall and atherosclerotic plaques with 360° real•time pictures can

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add much to the standard imaging techniques than CA.

Methods: It included 20 patientS wh9 had intem1cdiatc coronary lesions 507•0% diameter •• ' stenosis by QCA. QCA was perfom1cd by using automatic method for measuremeut of MLD.

I RSD. %DS then done IVUS at the site of angiographicilly defined MLD, we measured lumen I

area, EEMCSA, plaque area. %CSA stenosis MLD, %DS and plaque morphology.

Results: %DS by IVUS was 61.08 ± 3.713 (range 56% to 66.8%) and 56.38 (range 50-70%) by QCA (P< 0.001). MLD was 1.485 ± 0.33 by IVUS and 1.36 ± 0.35 by QCA %CSA stenosis was 80.92%± 4.795 by QCA and 84.9 ± 2.85% by IVUS (P< 0.001). Conclusions: QCA . tends to underestimate %DS and %CSA stenosis when compared with

IVUS. none of the lesions judged to be intcnncdiatc by QCA was tbund to be severe by IV US.