EVALUATION OF O-GLUTATHIONE S TRANSFERASE AS A MARKER OF HEPATOCELLULAR DAMAGE IN PATIENTS WITH CHRONIC HEPATITIS C

Abstract

The zucasurent of a-Glutathione S Transferase in serum or plasma S) has proved to probably be the most sensitive biochemical test available to A s%as.1 wt.t, t '')) monitor the effects of acute hepatic insults. ( I nn this study of chronic liver insults, a-Glutathione S Transferase levels were significantly higher in chronic hepatitis C patients than healthy controls 4$led to be a better indicator and more correlating witl histopathological changes in chronic HCV than other liver enzymes like ALT, AST, because it is more liver specific and of short plasma half Life.