HYPOLIPIDEMIC EFFECT OF SOME HERBS ON DIETARY INDUCED HYPERLIPIDEMIC RATS

Abstract

This work has been carried out to investigate the chemical and biological effects of dill, parsley and celery either herbs or essential oils. Rats used in the biological study, were fed basal diet for two weeks. The rats were divided randomly for two main groups. The first is the control, and the secon<! is hypercholesterolemic group which divided into to 13 subgroups according to the diet. The effect of these herbs and long term administrated essential oils . on the body weight gain, ratio of organs (liver, kidney, spleen, heart) to body weight were recorded. Blood samples were collected by withdrawing in zero time and 30 days from vein plexus eye and the serum was obtained. Total lipids, triglycerides, total cholesterol, HDL, LDL, AST, ALT and thyroid hormones were determined. Liver, kidney, heart and spleen were carefully separated, weighted and subjected to histopathological examination. The obtained results revealed that feeding parsley, celery and dill herbs showed to be the best treatment for lowering lipid constituents compared with those of oral administration of essential oil of the seeds of the previously mentioned herbs.