REGENERATIVE POTENTIAL OF A POROUS BONE MINERAL AND A BILAYER COLLAGEN MEMBRANE IN THE MANAGEMENT OF PERIODONTAL OSSEOUS DEFECTS

Abstract

The current investigation was conducted to evaluate clinically, radiographically and histologically three approaches used for the management of deep, interproximal, periodontal osseous defects in chronic periodontitis patients. The use of a bilayer collagen barrier was compared to that of anorganic bovine mineral when applied separately, or combined together. Accordingly, the study comprised two main sections; a clinical and radiographic section to evaluate treatment outcome in human subjects and a histologic section using an experimental dog model. A total number of eleven systemically healthy, chronic periodontitis patients were recruited for the clinical study. Prior to surgery, they were placed on a comprehensive oral hygiene program. Full-mouth scaling and root planing were performed. This phase lasted till the O'Leary plaque index approached a value of about 10% and the papillary bleeding index approached zero. Thirty periodontal osseous defects of matched severity were selected to participate in the study. Every ten defects were randomly assigned to one of the following groups: