The Role of PET/CT in Assessment of Response to Treatment of Lymphoma

Abstract

Currently, 18FDG PET-CT plays a great role in oncological diagnosis, staging and management. Over the past several years, it has gained attraction as the imaging technique of choice in lymphoma. This is attributed to its high sensitivity for tumor detection and add important functional information as it is not only reliable on nodal size to determine the presence or absence of malignancy. But, it allows the investigator to visualize and measure the intensity of residual metabolic activity within this node. Also, it has a major role in evaluation of the individual chemosensitivity and subsequently to adapt further therapy. Response assessment of lymphoma has mostly been achieved using visual criteria, like Deauville five-point scale. Nowadays, the use of functional quantitative parameters MTV and TLG rather than the universal metabolic quantitative parameter SUV as both may provide additional valuable information for prediction of tumor reaction to treatment.