Evaluation of the efficacy of Polydioxanone threads versus autologous plasma gel for infraorbital rejuvenation

Abstract

eriorbital hyperpigmentation, also known as dark eye circle, it affects both male and female. It’s an ill-defined lesion that presents as bilateral round or semicircular homogenous brown or dark brown pigmented macules in the periocular region. Several treatment modalities were proposed to improve and treat POH. Plasma gel is an autologous growth factors rich formula and is prepared from patients’ blood sample then injected into exact skin layers. On the hand, PDO threads insertion is an alternative in facial rejuvenation and facial aging. The current study aimed to compare between the efficacy and safety of PDO threads versus autologous plasma gel for infraorbital rejuvenation. Forty patients with POH were included and right eye was treated using PDO threads while left eye was treated using plasma gel. Assessment of treatment response was performed mainly by Antera 3D camera. PDO threads insertion and plasma gel revealed significant improvement in treated patients regarding wrinkles' size, depth, width, indentation index, texture roughness and average melanin concentration. However, plasma gel showed better response compared to PDO threads. Treatment with both modalities showed better response when it was continued for longer durations.