Browsing by Author Abouzid, Khaled


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Issue DateTitleAuthor(s)
Mar-2022Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessmentElgiushy, Hossam R; Mohamed, Sameh H; Sawaf, Hussein; Hassan, Zeinab; Abou-Taleb, Nageh A; El-Labbad, Eman M; Hassan, Ashraf S; Abouzid, Khaled A M; Abouzid, Khaled ; Ali Taha, Heba
Dec-2018Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modelingAdel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid 
8-Mar-2022Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluationMansour, Mai A; Oraby, Mamdouh A; Muhammad, Zeinab A; Lasheen, Deena ; Gaber, Hatem M; Khaled A M Abouzid 
2019Identification of novel pyrazole and benzimidazole based derivatives as PBP2a inhibitors: Design, synthesis, and biological evaluationShalaby, Menna-Allah; Dokla, Eman ; Serya, Rabah ; Abouzid, Khaled 
Jul-2013In silico design: extended molecular dynamic simulations of a new series of dually acting inhibitors against EGFR and HER2Ahmed, Marawan; Sadek, Maiada M; Abouzid, Khaled ; Wang, Feng
1-Dec-2021Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancerDokla, Eman ; Abdel-Aziz, Amal Kamal; Milik, Sandra N.; Mahmoud, Amr H.; Saadeldin, Mona Kamal; McPhillie, Martin J.; Minucci, Saverio; Khaled A M Abouzid 
2022Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: A case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitorsMilik, SN; Abdel-Aziz, AK; El-Hendawy, MM; El-Gogary, RI; Saadeldin, MK; Minucci, S; Klein, CD; Abouzid, Khaled 
1-Apr-2012Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivativesIsmail, Mohamed A H; Abou El Ella, Dalal ; Khaled A M Abouzid ; Mahmoud, Amr H
1-Sep-2020An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic propertiesMohamed, Sameh H; Elgiushy, Hossam R; Hammad, Sherif F; Abou-Taleb, Nageh A; A M Abouzid, Khaled; Abouzid, Khaled ; Hassan, Zeinab; Ali Taha, Heba
1-Sep-2011Labeling and Biological Evaluation of 99mTc-Cefotaxime for infective Inflammation DiagnosisM. A. Motaleb; A. A. El Mohty; M. A. El Garhy; Mohamed abdel Hamid Ismail; Abouzid, Khaled ; Tamer M. Sakr
15-Feb-2006Ligand design and synthesis of new imidazo[5,1-b]quinazoline derivatives as alpha1-adrenoceptor agonists and antagonistsIsmail, Mohamed A H; Aboul-Enein, Mohamed N Y; Abouzid, Khaled ; Serya, Rabah A T
1-Dec-2013Ligand design, synthesis and biological anti-HCV evaluations for genotypes 1b and 4a of certain 4-(3- & 4-[3-(3,5-dibromo-4-hydroxyphenyl)-propylamino] phenyl) butyric acids and 3-(3,5-dibromo-4-hydroxyphenyl)-propylamino- acetamidobenzoic acid estersIsmail, Mohamed Abdel Hamid; Mohamed, Nasser Saad; Dokla, Eman ; Khaled A M Abouzid 
2021Lipid polymer hybrid nanocarriers as a combinatory platform for different anti-SARS-CoV-2 drugs supported by computational studiesAbdel-Bar, Hend Mohamed; Abdallah, Inas A.; Fayed, Marwa A. A.; Moatasim, Yassmin; Mostafa, Ahmed; El-Behairy, Mohammed Farrag; Elimam, Hanan; Elshaier, Yaseen A. M. M.; Abouzid, Khaled 
2009Lonazolac analogues: molecular modeling, synthesis, and in vivo anti-inflammatory activityIsmail, MAH; Lehmann, J; Abou El Ella, D.A. ; Albohy, A; Abouzid, Khaled 
Nov-2017Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer ActivitiesGhith, Amna; Ismail, Nasser S M; Youssef, Khairia; Abouzid, Khaled 
2021Medicinal Chemistry Strategies Towards SO2 Donors as Research Tools and Potential TherapeuticsEl-Labbad, Eman M; Ji, Xingyue; Abouzid, Khaled ; Wang, Binghe
Jun-2014Molecular design and synthesis of 1,4-disubstituted piperazines as α(1)-adrenergic receptor blockersHussein, Mohammed M; Serya, Rabah ; Abdel Naby, Rana M; Al-Abd, Ahmed M; Saleh, Dalia O; El-Eraky, Wafaa I; Khaled A M Abouzid ; Abou El Ella, Dalal 
Oct-2013Molecular design and synthesis of HCV inhibitors based on thiazolone scaffoldAl-Ansary, Ghada H; Ismail, Mohamed A H; Abou El Ella, Dalal ; Eid, Sameh; Abouzid, Khaled 
Dec-2022Molecular design, synthesis and biological evaluation of novel 1,2,5-trisubstituted benzimidazole derivatives as cytotoxic agents endowed with ABCB1 inhibitory action to overcome multidrug resistance in cancer cellsAbdelhafiz, Abeer H A; Serya, Rabah A T; Lasheen, Deena S. ; Wang, Nessa; Sobeh, Mansour; Wink, Michael; Abouzid, Khaled 
Mar-2013Molecular design, synthesis and cell based HCV replicon assay of novel benzoxazole derivativesIsmail, M A H; Сиддик Адель Мухаммед ; Ismail, N S M; Abouzid, Khaled